Accolate

This page contains drug information on Accolate.
The information provided includes the following:
what is Accolate
the possible side effects of Accolate
what happens if you miss a dose of Accolate
what happens if you overdose with Accolate
the most important information about Accolate
how to use Accolate
other drugs that may affect Accolate
what to avoid while using Accolate

Generic Name: zafirlukast (za FIR loo cast)
Brand Names: Accolate

What is the most important information I should know about zafirlukast?

• Contact your doctor immediately if you experience nausea, unexplained fatigue or tiredness, itching, yellowing of the skin or eyes, flu-like symptoms, or upper left stomach pain. These may be early signs of liver problems.
• Zafirlukast will not stop an asthma attack that has already begun. It is used to prevent asthmatic attacks.
• Use zafirlukast on a regular basis for best results. It may take several weeks to get the maximum effect of this medication.
• Seek medical attention if you notice that you require more than your usual or more than the maximum amount of any asthma medication in a 24-hour period. An increased need for medication could be an early sign of a serious asthma attack.
• Discuss with your doctor the use of alcohol while taking zafirlukast. Alcohol and zafirlukast can both affect the liver.

What is zafirlukast?

• Zafirlukast is a leukotriene (loo-koe-try-een) inhibitor. Leukotrienes are substances in the body that are associated with the inflammation and constriction of airway muscles and the accumulation of fluid in the lungs, all of which occur during an asthma attack.
• Zafirlukast is used to prevent asthma attacks.
• Zafirlukast may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking zafirlukast?

Before taking zafirlukast, tell your doctor if you

• have liver disease; or
• drink alcohol.
• You may not be able to take zafirlukast, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Talk to your doctor before taking zafirlukast if you are taking warfarin (Coumadin), which is used to reduce the risk of blood clot formation. Taking these drugs together increases the risk of bleeding and special monitoring may be required.
• Zafirlukast is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
• Zafirlukast passes into breast milk and may harm a nursing baby. Do not take zafirlukast without first talking to your doctor if you are breast-feeding a baby.
• If you are over 60 years of age, you may be more likely to experience side effects from zafirlukast. You may require a lower dose of this medication.
• Zafirlukast is not approved for use by children younger than 5 years of age.

How should I take zafirlukast?

• Take zafirlukast exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take this medication on an empty stomach 1 hour before or 2 hours after a meal.
• Do not stop taking zafirlukast without first talking to your doctor. It may be some time before you begin to notice effects from this medication.
• Continue taking any other asthma medications, as directed by your doctor.
• Zafirlukast will not stop an asthma attack that has already begun. Keep another medication on hand to treat attacks.
• Seek medical attention if you notice that you require more than your usual or more than the maximum amount of any asthma medication in a 24-hour period. An increased need for medication could be an early sign of a serious asthma attack.
• Store zafirlukast at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take the next regularly scheduled dose as directed. Do not take a double dose of this medication.

What happens if I overdose?

• Seek emergency medical attention.
• The symptoms of an overdose of zafirlukast are unknown.

What should I avoid while taking zafirlukast?

• Avoid items or activities that are known allergens or that make your symptoms worse. Clean areas where dust or pet fur may aggravate your condition.
• Discuss with your doctor the use of alcohol while taking zafirlukast. Alcohol and zafirlukast can both affect the liver.

What are the possible side effects of zafirlukast?

• Contact your doctor immediately if you experience nausea, unexplained fatigue or tiredness, itching, yellowing of the skin or eyes, flu-like symptoms, or upper left stomach pain. These may be early signs of liver problems.
• If you experience any of the following serious side effects, stop taking zafirlukast and seek emergency medical attention or contact your doctor immediately: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); · numbness, tingling, or pain; · a rash or unexplained open sores or bruising; or · worsening respiratory symptoms.
• Other, less serious side effects may be more likely to occur. Continue to take zafirlukast and talk to your doctor if you experience · dizziness; · headache; or · nausea, vomiting, or diarrhea.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

Actonel

This page contains drug information on Actonel.
The information provided includes the following:
what is Actonel
the possible side effects of Actonel
what happens if you miss a dose of Actonel
what happens if you overdose with Actonel
the most important information about Actonel
how to use Actonel
other drugs that may affect Actonel
what to avoid while using Actonel

Generic Name: risedronate (rih SED ro nayt) Brand Names: Actonel

What is the most important information I should know about risedronate?

• Do not take an risedronate tablet if you cannot sit upright or stand for at least 30 minutes. Risedronate can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking this medication.
• Take the risedronate tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine.
• Take each dose with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking a risedronate tablet.
• For at least the first 30 minutes after taking a risedronate tablet, do not lie down or recline; do not eat or drink anything other than plain water; and do not take any other medicines including vitamins, calcium, or antacids.
• Some people using medicines similar to risedronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and a pre-existing dental problems.
• Risedronate is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.

What is risedronate?

• Risedronate is in the group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body. Risedronate slows bone loss while increasing bone mass, which may prevent bone fractures.
• Risedronate is used to treat or prevent postmenopausal osteoporosis and steroid-induced osteoporosis. Risedronate is also used to treat Paget's disease of bone.
• Risedronate may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking risedronate?

Do not take a risedronate tablet if you cannot sit upright or stand for at least 30 minutes. Risedronate can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking this medication.

Before using risedronate, tell your doctor if you have:

• low blood calcium (hypocalcemia);
• a vitamin D deficiency;
• kidney disease; or
• an ulcer in your stomach or esophagus.
• If you have any of these conditions, you may not be able to use risedronate, or you may need a dosage adjustment or special tests during treatment.
• Some people using medicines similar to risedronate have developed bone loss in the jaw, also called osteonecrosis of the jaw. Symptoms of this condition may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums.
• You may be more likely to develop osteonecrosis of the jaw if you have cancer or have been treated with chemotherapy, radiation, or steroids. Other conditions associated with osteonecrosis of the jaw include blood clotting disorders, anemia (low red blood cells), and dental surgery or pre-existing dental problems.
• FDA pregnancy category C. This medication may be harmful to an unborn baby and should not be used by a woman who is pregnant. Tell your doctor if you become pregnant during treatment.
• It is not known whether risedronate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take risedronate?

• Take risedronate exactly as it was prescribed for you. Do not use the medication in larger amounts or for longer than recommended by your doctor.
• Risedronate tablets are taken either once each day or once each week.
• Take the risedronate tablet first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take a risedronate tablet only once a week, take it on the same day each week and always first thing in the morning.
• Take each risedronate tablet with a full glass (6 to 8 ounces) of water. Use only plain water (not mineral water) when taking a risedronate tablet.
• Do not crush, chew, or suck the risedronate tablet. Swallow the pill whole.
• After taking a risedronate tablet, carefully follow these instructions:
• Do not lie down or recline for at least 30 minutes after taking risedronate.
• Do not eat or drink anything other than plain water.
• Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking risedronate. It may be best to take your other medicines at a different time of the day. Talk with your doctor about the best dosing schedule for your other medicines.
• To be sure this medication is helping your condition, your bone mineral density will need to be tested on a regular basis. It is important that you not miss any scheduled visits to your doctor.
• Risedronate is only part of a complete program of treatment that may also include diet changes, exercise, and taking calcium and vitamin supplements. Follow your diet, medication, and exercise routines very closely.
• Store risedronate tablets at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you take risedronate tablets once daily: If you forget to take this medicine first thing in the morning, do not take it later in the day. Wait until the following morning to take the medicine and skip the missed dose. Do not take take two (2) tablets in one day.
• If you take risedronate tablets once a week: If you forget to take risedronate on your scheduled day, take it first thing in the morning on the day after you remember the missed dose. Then return to your regular weekly schedule on your chosen dose day. Do not take take two (2) tablets in one day.

What happens if I overdose?

• Seek emergency medical attention if you think you have used too much of this medicine. Drink a full glass of milk and call your local poison control left or emergency room right away. Do not make yourself vomit and do not lie down.
• Symptoms of a risedronate overdose may include nausea, heartburn, stomach pain, diarrhea, muscle cramps, numbness or tingling, tight muscles in your face, seizure (convulsions), irritability, and unusual thoughts or behavior.

What should I avoid while taking risedronate?

• Do not take any other medicines including vitamins, calcium, or antacids for at least 30 minutes after taking an risedronate tablet.
• Do not lie down for at least 30 minutes after you take a risedronate tablet.

What are the possible side effects of risedronate?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Stop using risedronate and call your doctor at once if you have any of these serious side effects:

• chest pain;
• difficulty or pain when swallowing;
• pain or burning under the ribs or in the back;
• new or worsening heartburn;
• severe joint, bone, or muscle pain; or
• jaw pain, numbness, or swelling.
• Continue using risedronate and talk with your doctor if you have any of these less serious side effects:
• mild heartburn or stomach upset;
• diarrhea, gas, or constipation;
• mild joint or back pain; or
• headache.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect risedronate?

• Antacids, supplements, or medicines that contain aluminum, calcium, magnesium, or other minerals can interfere with how your body absorbs risedronate. If you use these other medicines, do not that take them for at least 30 minutes after taking a risedronate tablet.
• Before using risedronate, tell your doctor if you also use aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as celecoxib (Celebrex), diclofenac (Voltaren), diflunisal (Dolobid), ibuprofen (Motrin, Advil), indomethacin, ketoprofen (Orudis), ketorolac (Toradol), naproxen (Aleve, Naprosyn), piroxicam (Feldene), and others.
• There may be other drugs that can affect risedronate. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Advair Diskus

This page contains drug information on Advair Diskus.
The information provided includes the following:
what is Advair Diskus
the possible side effects of Advair Diskus
what happens if you miss a dose of Advair Diskus
what happens if you overdose with Advair Diskus
the most important information about Advair Diskus
how to use Advair Diskus
other drugs that may affect Advair Diskus
what to avoid while using Advair Diskus

Generic Name: fluticasone and salmeterol (floo TIK a sone, sal ME te rol)
Brand Names: Advair Diskus

What is the most important information I should know about fluticasone and salmeterol inhalation?

• Do not use fluticasone and salmeterol inhalation to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use another, faster-acting inhalation medication to treat an asthma attack.
• This medication can lower the blood cells that help your body fight infections. This can make it easier for you to get sick. Avoid being near people who are sick or have infections. Contact your doctor if you have been exposed to someone with measles or chicken pox.
• Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack.
• Salmeterol is has been shown to increase the risk of asthma-related death. It is critical that you use only the prescribed dose of this medicine and follow all patient instructions for safe use of the medication. Talk with your doctor about your individual risks and benefits in using fluticasone and salmeterol.

What is fluticasone and salmeterol inhalation?

• Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation. Salmeterol is a bronchodilator. It works by relaxing muscles in the airways to improve breathing.
• Fluticasone and salmeterol inhalation is used to prevent asthma attacks. It will not treat an asthma attack that has already begun. Fluticasone and salmeterol inhalation is also used to treat chronic obstructive pulmonary disease (COPD) associated with chronic bronchitis.
• Fluticasone and salmeterol may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before using fluticasone and salmeterol?

• Before using this medication, tell your doctor if you have been sick or had an infection of any kind. You may not be able to use fluticasone and salmeterol inhalation until you are well.
• Salmeterol is a drug that has been shown to increase the risk of asthma-related death. It is critical that you use only the prescribed dose of this medicine and follow all patient instructions for safe use of the medication. Talk with your doctor about your individual risks and benefits in using fluticasone and salmeterol.
• Before using fluticasone and salmeterol, tell your doctor if you have:
• a food or drug allergy;
• heart disease or high blood pressure;
• epilepsy or other seizure disorder;
• diabetes;
• glaucoma;
• tuberculosis;
• a thyroid disorder; or
• liver disease.
• If you have any of these conditions, you may not be able to use fluticasone and salmeterol, or you may need a dosage adjustment or special tests during treatment.
• FDA pregnancy category C. This medication may be harmful to an unborn baby and should not be used by a woman who is pregnant. Tell your doctor if you become pregnant during treatment.
• It is not known whether this medication passes into breast milk or if it could harm a nursing baby. Do not use fluticasone and salmeterol inhalation without telling your doctor if you are breast-feeding a baby.
• Fluticasone and salmeterol inhalation can affect growth in children. Talk with your doctor if you think your child is not growing at a normal rate while using this medication.
• Do not give this medication to a child younger than 4 years old.
• Long-term use of steroids may lead to bone loss (osteoporosis), especially if you smoke, if you do not exercise, if you do not get enough vitamin D or calcium in your diet, or if you have a family history of osteoporosis. Talk with your doctor about your risk of osteoporosis.

How should I use fluticasone and salmeterol inhalation?

• Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor.
• Do not use fluticasone and salmeterol inhalation to treat an asthma attack that has already begun. It will not work fast enough to reverse your symptoms. Use another, faster-acting inhalation medication to treat an asthma attack.
• Asthma is usually treated with a combination of different drugs. To best treat your condition, use all of your medications as directed by your doctor. Do not change your doses or medication schedule without advice from your doctor.
• If you use this medication to treat COPD, do not use the medicine for longer than 6 months unless your doctor has told you to.
• Advair Diskus is a powder form of fluticasone and salmeterol that comes with a special inhaler device preloaded with blister packs containing measured doses of the medicine. The device opens and loads a blister each time you use the inhaler. This device is not to be used with a spacer.
• This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
• To reduce the chance of developing a yeast infection in your mouth, rinse with water after using fluticasone and salmeterol inhalation. Do not swallow.
• It is important to use fluticasone and salmeterol inhalation regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
• If you were switched from an oral (taken by mouth) steroid to fluticasone and salmeterol inhalation, you may need to go back to taking the oral medicine if you are under stress or have an asthma attack or other medical emergency. Carry an identification card or wear a medical alert ID to let others know that you may need an oral steroid in an emergency.
• Seek medical attention if you think any of your asthma medications are not working as well as usual. An increased need for medication could be an early sign of a serious asthma attack. If you use a peak flow meter at home, call your doctor if your numbers are lower than normal.
• Store this medication at room temperature away from moisture and heat. Keep the medicine canister away from high heat, such as open flame or in a car on a hot day. The canister may explode if it gets too hot.
• Do not reuse the Diskus device. Throw it away 1 month after you have taken it out of the foil pouch, or if the dose indicator shows a zero, whichever comes first. Each Diskus device contains 60 doses.

What happens if I miss a dose?

• Use the medication as soon as you remember. If it is almost time for the next dose, skip the missed dose and wait until your next regularly scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

• Seek emergency medical attention if you think you have used too much of this medicine.
• Symptoms of a fluticasone and salmeterol overdose may include angina or chest pain, fast or irregular heartbeats, seizures, tremor, weakness, headache, nausea, and vomiting.

What should I avoid while using fluticasone and salmeterol inhalation?

• Do not use a second form of salmeterol (such as Serevent) or use a similar inhaled bronchodilator such as formoterol (Foradil) unless your doctor has told you to.
• Fluticasone and salmeterol inhalation can lower the blood cells that help your body fight infections. This can make it easier for you to get sick from being around others who are ill. Avoid being near people who are sick or have infections. Contact your doctor if you have been exposed to someone with measles or chicken pox.
• Do not exhale or blow into the Diskus device. Do not take the device apart or allow it to get wet.

What are the possible side effects of fluticasone and salmeterol inhalation?

• Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
• Call your doctor at once if you have any of these serious side effects:
• weakness, tired feeling, nausea, loss of appetite, weight loss;
• chest pain, fast or pounding heartbeats, excitement or restless feeling;
• seizure (convulsions), feeling light-headed, fainting;
• wheezing, choking, or other breathing problems after using this medication;
• skin rash, bruising, severe tingling, numbness, pain, muscle weakness;
• changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist); or
• worsening asthma symptoms.
• Other, less serious side effects may be more likely to occur, such as:
• headache;
• dryness in your mouth, nose, or throat;
• white patches or sores inside your mouth or on your lips;
• nausea, vomiting, diarrhea, upset stomach;
• stuffy nose, sinus pain, cough, sore throat; or
• hoarseness or deepened voice.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect fluticasone and salmeterol inhalation?

• Before using fluticasone and salmeterol inhalation, tell your doctor if you are using any of the following drugs:
• amiodarone (Cordarone);
• a diuretic or "water pill";
• HIV medicines such as ritonavir (Norvir), indinavir (Crixivan), nelfinavir (Viracept);
• an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);
• antidepressants such as amitriptyline (Elavil), nortriptyline (Pamelor), desipramine (Norpramin), or imipramine (Tofranil);
• certain antibiotics such as ketoconazole (Nizoral), itraconazole (Sporanox), clarithromycin (Biaxin), erythromycin (E-Mycin, Ery-Tab, E.E.S.); or
• medicines for depression such as fluoxetine (Prozac), or fluvoxamine (Luvox).
• If you are using any of these drugs, you may not be able to use fluticasone and salmeterol, or you may need dosage adjustments or special tests during treatment.
• There may be other drugs not listed that can affect fluticasone and salmeterol inhalation. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Aldactone

This page contains drug information on Aldactone.
The information provided includes the following:
what is Aldactone
the possible side effects of Aldactone
what happens if you miss a dose of Aldactone
what happens if you overdose with Aldactone
the most important information about Aldactone
how to use Aldactone
other drugs that may affect Aldactone
what to avoid while using Aldactone

Generic Name: spironolactone (speer oh no LAK tone)
Brand Names: Aldactone, Spironol

What is the most important information I should know about spironolactone?
• To reduce nighttime urination, take spironolactone early in the day unless otherwise directed by your doctor.
• Take spironolactone with food or milk to lessen stomach upset.
• Do not use salt substitutes or low-sodium milk products that contain potassium while taking spironolactone. These products could cause high levels of potassium in your blood. Ask your doctor or pharmacist about any salt substitutes you are taking.

What is spironolactone?
• Spironolactone is in a class of drugs called potassium-sparing diuretics (water pill). It is used to reduce the amount of fluid in your body without causing the loss of potassium.
• Spironolactone is used to treat edema (swelling) and hypertension (high blood pressure).
• Spironolactone is also used to treat potassium deficiency and hyperaldosteronism (a hormonal disorder).
• Spironolactone may also be used for purposes other than those listed in this medication guide.

Who should not take spironolactone?
• Before taking spironolactone, tell your doctor if you · have kidney disease; · have liver disease; · have diabetes mellitus; · have high levels of potassium in your blood; or · are taking a potassium supplement or an angiotensin-converting-enzyme inhibitor (ACE inhibitor) such as captopril (Capoten), benazepril (Lotensin), lisinopril (Prinivil, Zestril), enalapril (Vasotec), or others.
• You may not be able to take spironolactone, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Spironolactone is in the FDA pregnancy category D. This means that spironolactone is known to harm an unborn baby. Do not take spironolactone if you are pregnant.
• It is not known whether spironolactone passes into breast milk. Do not take spironolactone without first talking to your doctor if you are breast-feeding a baby.

How should I take spironolactone?
• Take spironolactone exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take spironolactone with food or milk to lessen stomach upset.
• To reduce nighttime urination, take spironolactone early in the day unless otherwise directed by your doctor.
• Do not stop taking spironolactone suddenly even if you feel better. Stopping suddenly could make your condition worse.
• Store spironolactone at room temperature away from moisture and heat.

What happens if I miss a dose?
• Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the dose you missed and take only your next regularly scheduled dose as directed. Do not take a double dose of this medication.

What happens if I overdose?
• Seek emergency medical attention.
• Symptoms of a spironolactone overdose include an irregular heartbeat, lethargy, fatigue, weakness, drowsiness, dizziness, confusion, shortness of breath, nausea, and vomiting.

What should I avoid while taking spironolactone?
• Do not use salt substitutes or low-sodium milk products that contain potassium while taking spironolactone. These products could cause high levels of potassium in your blood. Ask your doctor or pharmacist about any salt substitutes you are taking.

What are the possible side effects of spironolactone?
• Stop taking spironolactone and seek emergency medical attention if you experience any of the following serious side effects: · an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); · an irregular heartbeat, shortness of breath, fatigue, confusion, weakness, numbness, or tingling (caused by high levels of potassium in your blood); or · decreased urination.
• Other, less serious side effects may be more likely to occur. Continue to take spironolactone and talk to your doctor if you experience · unusual headache or dizziness; · nausea, diarrhea, or a decrease in appetite; · dry mouth; · bloating; · muscle cramps; or · lowering of the voice, excessive hair growth, or enlarged breasts.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect spironolactone?
• Before taking spironolactone tell your doctor if you are taking any of the following medications: · lithium (Lithobid, Eskalith, others); · probenecid (Benemid); · a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen (Motrin, Advil, Nuprin), naproxen (Naprosyn, Anaprox, Aleve), ketoprofen (Orudis, Orudis KT, Oruvail), indomethacin (Indocin), diclofenac (Cataflam, Voltaren), etodolac (Lodine), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), tolmetin (Tolectin), fenoprofen (Nalfon), ketorolac (Toradol), or flurbiprofen (Ansaid); or · a diabetes medication such as glipizide (Glucotrol), glyburide (Micronase, Glynase, Diabeta), chlorpropamide (Diabinese), tolazamide (Tolinase), tolbutamide (Orinase), and others.
• You may not be able to take spironolactone, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medications listed above.
• Also, before taking spironolactone, tell your doctor if you are taking any other medicine to treat high blood pressure, water retention, heart problems, prostate problems, or another condition. Some medicines used to treat these conditions may interact with spironolactone and the effects on your heart may be increased.
• Drugs other than those listed here may also interact with spironolactone. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Ansaid

This page contains drug information on Ansaid.
The information provided includes the following:
what is Ansaid
the possible side effects of Ansaid
what happens if you miss a dose of Ansaid
what happens if you overdose with Ansaid
the most important information about Ansaid
how to use Ansaid
other drugs that may affect Ansaid
what to avoid while using Ansaid

Generic Name: flurbiprofen (FLURE bih proe fin)
Brand Names: Ansaid

What is the most important information I should know about flurbiprofen?

• Take flurbiprofen with food, milk, or an antacid to lessen stomach upset.
• Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to flurbiprofen (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, flurbiprofen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking flurbiprofen if you drink more than 3 alcoholic beverages a day.

What is flurbiprofen?

• Flurbiprofen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Flurbiprofen works by reducing hormones that cause inflammation and pain in the body.
• Flurbiprofen is used to reduce the pain, inflammation, and stiffness caused by arthritis.
• Flurbiprofen may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking flurbiprofen?

• Before taking this medication, tell your doctor if you
• have an allergy to aspirin or any other NSAIDs,
• have an ulcer or bleeding in your stomach,
• drink more than three alcoholic beverages a day,
• have liver or kidney disease,
• have a coagulation (bleeding) disorder,
• have congestive heart failure,
• have fluid retention,
• have heart disease, or
• have high blood pressure.
• You may not be able to take flurbiprofen, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• It is not known whether flurbiprofen will be harmful to an unborn baby. Flurbiprofen should not be taken in late pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take flurbiprofen without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• It is not known whether flurbiprofen passes into breast milk. Do not take this drug without first talking to your doctor if you are breast-feeding.

How should I take flurbiprofen?

• Take flurbiprofen exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take each dose with food, milk, or an antacid to lessen stomach upset.
• Store flurbiprofen at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you are taking flurbiprofen on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.
• If you are taking flurbiprofen as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a flurbiprofen overdose may include nausea, vomiting, abdominal pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, sweating, numbness or tingling, little or no urine production, and slow breathing.

What should I avoid while taking flurbiprofen?

• Avoid prolonged exposure to sunlight. Flurbiprofen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, flurbiprofen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking flurbiprofen if you drink more than 3 alcoholic beverages a day.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to flurbiprofen (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of flurbiprofen?

• Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
• If you experience any of the following serious side effects, stop taking flurbiprofen and seek medical attention or contact your doctor immediately:
• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• muscle cramps, numbness, or tingling;
• ulcers (open sores) in the mouth;
• rapid weight gain (fluid retention);
• seizures;
• decreased hearing or ringing in the ears;
• yellowing of the skin and eyes (jaundice); or
• abdominal cramping, indigestion, or heartburn.
• Other, less serious side effects may be more likely to occur. Continue to take flurbiprofen and talk to your doctor if you experience
• dizziness or headache;
• nausea, diarrhea, or constipation;
• depression;
• fatigue or weakness;
• dry mouth; or
• irregular menstrual periods.
• Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect flurbiprofen?

• Before taking flurbiprofen, tell your doctor if you are taking any of the following drugs:
• aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, others);
• another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), ibuprofen (Motrin, Advil, others), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Anaprox, others), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
• an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, flurbiprofen, or ketoprofen;
• an anticoagulant (blood thinner) such as warfarin (Coumadin);
• a steroid such as prednisone (Deltasone);
• insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), and others;
• probenecid (Benemid);
• lithium (Eskalith, Lithobid, others); or
• bismuth subsalicylate in drugs such as Pepto-Bismol.
• You may not be able to take flurbiprofen, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.
• Drugs other than those listed here may also interact with flurbiprofen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

What is

Arava

Who should not take Arava?

You must not take Arava if you are pregnant or a woman of childbearing age not using reliable contraception.

Special Warning(s) with Arava:

For Women:

You must not take Arava if you are pregnant or a woman of childbearing age not using reliable contraception because in animal studies Arava has been shown to cause birth defects to the fetus. You must avoid becoming pregnant while being treated with Arava. If you suspect or find out that you are pregnant while taking Arava, call your health care provider right away. After stopping Arava treatment, you must complete the drug elimination procedure before becoming pregnant because Arava stays in the body a long time. You should not breast-feed if you are taking Arava.

For Men:
If there is any possibility your partner could become pregnant, you should stop Arava treatment and go through the drug elimination procedure prescribed by your doctor.

For All Patients:
• Rare cases of severe liver injury, including death, have been reported by patients taking Arava. Your doctor will conduct liver tests before you start taking Arava and will check your liver's response to Arava monthly for the first six months and then, if unchanged, every 6 to 8 weeks thereafter.
• Interstitial lung disease (an inflammation of lung tissue) has been reported in patients taking Arava. If you develop new or worsening symptoms such as cough or trouble breathing, with or without a fever, notify your health care provider immediately.

General Precautions with Arava:
If you have the following conditions or if you are being treated with medications that can be harmful to your liver, Arava may not be right for you:

• liver disease including hepatitis B or hepatitis C
• kidney problems
• severe immune system disorders, bone marrow disorders or uncontrolled infection.
• What are some possible side effects of Arava? (This is NOT a complete list of side effects reported with Arava. Your health care provider can discuss with you a more complete list of side effects.)
• diarrhea
• elevated liver enzymes
• hair loss
• skin rash
• mouth sores
• unusual tiredness
• abdominal pain

Celebrex

This page contains drug information on Celebrex.
The information provided includes the following:
what is Celebrex
the possible side effects of Celebrex
what happens if you miss a dose of Celebrex
what happens if you overdose with Celebrex
the most important information about Celebrex
how to use Celebrex
other drugs that may affect Celebrex
what to avoid while using Celebrex

Generic Name: celecoxib (oral) (seh leh COCK sib)
Brand Names: Celebrex

What is the most important information I should know about celecoxib?

• Recent information suggests a possible increased risk for heart attack and stroke in patients taking celecoxib. The relevance of this information is still not known. Ask your doctor if celecoxib is right for you.
• Do not take celecoxib without first talking to your doctor if you have experienced asthma, hives, or an allergic reaction after taking a sulfa-based medication such as sulfamethoxazole (Bactrim, Septra, Gantanol, and others) or sulfisoxazole (Gantrisin); aspirin; or another NSAID such as valdecoxib (Bextra), ibuprofen (Motrin, Advil, Nuprin, and others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine, Lodine XL), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin). You may experience a similar reaction to celecoxib.
• Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.

What is celecoxib?

• Celecoxib is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Celecoxib works by reducing substances that cause inflammation, pain, and fever in the body.
• Celecoxib is used to reduce pain, inflammation, and stiffness caused by osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Celecoxib is also used to reduce the number of adenomatous colorectal polyps in familial adenomatous polyposis (FAP), to treat acute pain, and to treat pain associated with menstruation.
• Celecoxib may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking celecoxib?

Recent information suggests a possible increased risk for heart attack and stroke in patients taking celecoxib. The relevance of this information is still not known. Ask your doctor if celecoxib is right for you.

Do not take celecoxib without first talking to your doctor if you have experienced asthma, hives, or an allergic reaction after taking a sulfa-based medication such as sulfamethoxazole (Bactrim, Septra, Gantanol, and others) or sulfisoxazole (Gantrisin); aspirin; or another NSAID such as valdecoxib (Bextra), ibuprofen (Motrin, Advil, Nuprin, and others), naproxen (Aleve, Naprosyn, Anaprox), ketoprofen (Orudis KT, Orudis, Oruvail), diclofenac (Voltaren, Cataflam), diflunisal (Dolobid), etodolac (Lodine, Lodine XL), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin). You may experience a similar reaction to celecoxib.

Before taking celecoxib, tell your doctor if you

• smoke;
• drink alcohol;
• have an ulcer or bleeding in the stomach;
• have liver disease;
• have kidney disease;
• have coronary artery disease (CAD);
• have arteriosclerotic disease (hardening of the arteries, clogged or blocked arteries);
• have asthma;
• have congestive heart failure;
• have fluid retention;
• have heart disease;
• have high blood pressure;
• have a coagulation (bleeding) disorder or are taking an anticoagulant (blood thinner) such as warfarin (Coumadin); or
• are taking a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others.

You may not be able to take celecoxib, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions, or are taking any of the medicines, listed above.

Celecoxib is in the FDA pregnancy category C. This means that it is not known whether it will harm an unborn baby. Celecoxib should not be taken late in pregnancy (the third trimester) because it may affect the formation of the baby's heart. Do not take celecoxib without first talking to your doctor if you are pregnant.

It is not known whether celecoxib passes into breast milk. Do not take celecoxib without first talking to your doctor if you are breast-feeding.

If you are over the age of 65 years, you may be more likely to experience side effects from celecoxib. You may require a lower dosage or special monitoring during your therapy.

How should I take celecoxib?

• Take celecoxib exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Celecoxib can be taken with or without food or milk. Follow your doctor's instructions.
• Your doctor may want you to have blood tests or other medical evaluations during treatment with celecoxib to monitor progress and side effects.
• Store celecoxib at room temperature away from moisture and heat.

What happens if I miss a dose?

• Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose as directed. Do not take a double dose of this medication unless your doctor directs otherwise.

What happens if I overdose?

• Seek emergency medical attention.
• Symptoms of a celecoxib overdose include drowsiness, nausea, vomiting, stomach pain, dizziness, headache, ringing in the ears, blurred vision, little or no urine production, slow breathing, and coma.

What should I avoid while taking celecoxib?

• There are no restrictions on food, beverages, or activity while taking celecoxib unless otherwise directed by your doctor.

What are the possible side effects of celecoxib?

Notify your doctor immediately if you develop abdominal pain, tenderness, or discomfort; nausea; bloody vomit; bloody, black, or tarry stools; unexplained weight gain; swelling or water retention; fatigue or lethargy; a skin rash; itching; yellowing of the skin or eyes;"flu-like" symptoms; or unusual bruising or bleeding. These symptoms could be early signs of dangerous side effects.

If you experience any of the following serious side effects, stop taking celecoxib and seek medical treatment or call your doctor immediately:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);

Other, less serious side effects may be more likely to occur. Continue to take celecoxib and talk to your doctor if you experience

• flatulence or diarrhea;
• dizziness;
• headache; or
• insomnia.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect celecoxib?

Before taking celecoxib, tell your doctor if you are taking any of the following drugs:

• aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, Bayer Select Backache Formula, others);
• an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, naproxen, or ketoprofen;
• a diuretic (water pill) such as furosemide (Lasix), hydrochlorothiazide (HydroDiuril, others), chlorothiazide (Diuril, others), chlorthalidone (Hygroton, Thalitone), and others;
• an angiotensin-converting-enzyme inhibitor (ACE inhibitor) such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), quinapril (Accupril), and others;
• a steroid medicine such as prednisone (Deltasone and others), methylprednisolone (Medrol and others), prednisolone (Prelone, Pediapred, and others), and others;
• an anticoagulant (blood thinner) such as warfarin (Coumadin);
• lithium (Eskalith, Lithobid, others); or
• fluconazole (Diflucan).

You may not be able to take celecoxib, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with celecoxib. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines including vitamins, minerals, and herbal products.

Feldene
This page contains drug information on Feldene.
The information provided includes the following:
what is Feldene
the possible side effects of Feldene
what happens if you miss a dose of Feldene
what happens if you overdose with Feldene
the most important information about Feldene
how to use Feldene
other drugs that may affect Feldene
what to avoid while using Feldene

Generic Name: piroxicam (peer OX ih kam)
Brand Names: Feldene

What is the most important information I should know about piroxicam?

• Take piroxicam with food, milk, or an antacid to lessen stomach upset.
• Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to piroxicam (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, piroxicam may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking piroxicam if you drink more than 3 alcoholic beverages a day.

What is piroxicam?

• Piroxicam is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Piroxicam works by reducing hormones that cause inflammation and pain in the body.
• Piroxicam is used to reduce the pain, inflammation, and stiffness caused by rheumatoid arthritis and osteoarthritis.
• Piroxicam may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking piroxicam?

Before taking this medication, tell your doctor if you

• have an allergy to aspirin or any other NSAIDs,
• have an ulcer or bleeding in your stomach,
• drink more than three alcoholic beverages a day,
• have liver disease,
• have kidney disease,
• have a coagulation (bleeding) disorder,
• have congestive heart failure,
• have fluid retention,
• have heart disease, or

You may not be able to take piroxicam, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

It is not known whether piroxicam will be harmful to an unborn baby. Piroxicam should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take piroxicam without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether piroxicam passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take piroxicam?

• Take piroxicam exactly as directed. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take piroxicam with food, milk, or an antacid to lessen stomach upset.
• Store piroxicam at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you are taking piroxicam on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.
• If you are taking piroxicam as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a piroxicam overdose include nausea, vomiting, stomach pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, sweating, numbness or tingling, little or no urine production, and slow breathing.

What should I avoid while taking piroxicam?

• Avoid prolonged exposure to sunlight. Piroxicam may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, piroxicam may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking piroxicam if you drink more than 3 alcoholic beverages a day.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to piroxicam (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of piroxicam?

Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.

If you experience any of the following serious side effects, stop taking piroxicam and seek medical treatment or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• muscle cramps, numbness, or tingling;
• ulcers (open sores) in the mouth;
• rapid weight gain (fluid retention);
• seizures;
• decreased hearing or ringing in the ears;
• yellowing of your skin or eyes (jaundice); or
• abdominal cramping, heartburn, or indigestion.

Other, less serious side effects may be more likely to occur. Continue to take piroxicam and talk to your doctor if you experience

• dizziness or headache;
• nausea, diarrhea, or constipation;
• depression;
• fatigue or weakness;
• dry mouth; or
• irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect piroxicam?

Before taking piroxicam, tell your doctor if you are taking any of the following drugs:

• aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, others);
• another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Motrin, Advil, others), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), oxaprozin (Daypro), naproxen (Aleve, Anaprox, Naprosyn, Naprelan, others), sulindac (Clinoril), or tolmetin (Tolectin);
• an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, piroxicam, or ketoprofen;
• an anticoagulant (blood thinner) such as warfarin (Coumadin);
• a steroid such as prednisone (Deltasone);
• insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), and others;
• probenecid (Benemid);
• lithium (Eskalith, Lithobid, others); or
• bismuth subsalicylate in drugs such as Pepto-Bismol.

You may not be able to take piroxicam, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with piroxicam. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Fosamax
This page contains drug information on Fosamax.
The information provided includes the following:
what is Fosamax
the possible side effects of Fosamax
what happens if you miss a dose of Fosamax
what happens if you overdose with Fosamax
the most important information about Fosamax
how to use Fosamax
other drugs that may affect Fosamax
what to avoid while using Fosamax

Generic Name: alendronate (a LEN droe nate)
Brand Names: Fosamax

What is the most important information I should know about alendronate?

• Some forms of alendronate are taken once a day. Others are taken only once a week. It is very important that you follow your doctor's directions. If you take alendronate once a week, take it on the same day each week.
• After swallowing the tablet or oral solution, do not lie down, remain fully upright sitting, standing or walking, for at least 30 minutes and until after you have eaten.
• Do not take alendronate at bedtime or before getting up for the day.
• Do not crush, chew, or suck the tablets. Swallow them whole.

What is alendronate?

• Alendronate is a compound that alters the cycle of bone formation and breakdown in the body. Alendronate increases new bone formation.
• Alendronate is used to treat and prevent osteoporosis and to treat Paget's disease. Alendronate is also used to treat osteoporosis that is caused by treatment with a corticosteroid.
• Alendronate may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking alendronate?

Before taking alendronate, tell your doctor if you

• have a problem swallowing, such as a narrowing of the esophagus;
• have esophageal ulcers or an esophageal disease;
• have a condition that causes low levels of calcium in the body;
• have kidney disease;
• have stomach ulcers or other stomach or digestive problems; or
• are unable to stand or sit upright for at least 30 minutes.

You may not be able to take alendronate, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Alendronate is in the FDA pregnancy category C. This means that it is not known whether alendronate will be harmful to an unborn baby. Do not take alendronate without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether alendronate passes into breast milk. Do not take alendronate without first talking to your doctor if you are breast-feeding a baby.

How should I take alendronate?

• Take alendronate exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
• Some forms of alendronate are taken once a day. Others are taken only once a week. It is very important that you follow your doctor's directions. If you take alendronate once a week, take it on the same day each week.
• Take alendronate first thing in the morning, at least 30 minutes before you eat any food or drink any liquid (other than plain water). This timing is very important for getting the maximum amount of medication from each dose. Foods and beverages greatly decrease the effect of alendronate.
• To ensure that you get a correct dose, measure the alendronate oral suspension with a dose-measuring spoon, dropper, or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
• Take each tabet dose with a full glass (6 to 8 ounces) of tap water or bottled water. Follow each dose of oral solution with at least 2 ounces (one quarter cup) of water. Taking each dose with a full glass of water will ensure proper swallowing of the medication and reduce the risk of mouth or throat irritation. Do not take this medication with mineral water, juice, or any other beverage.
• Do not crush, chew, or suck the tablets. Swallow them whole.
• After swallowing the tablet or oral solution, do not lie down. Remain fully upright sitting, standing or walking, for at least 30 minutes and until after you have eaten.
• Do not take alendronate at bedtime or before getting up for the day.
• If you have difficulty or pain upon swallowing, chest pain, or new or worsening heartburn, stop taking alendronate and call your doctor.
• It is important that you continue taking alendronate for as long as your doctor prescribes it. Alendronate can treat or prevent osteoporosis only if you continue to take it.
• Store alendronate at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you take alendronate every day and you miss a dose, skip that dose and take the next regularly scheduled dose the following day. Missing one dose will not affect your treatment. Do not take two tablets at the same time.
• If you take alendronate once a week and you miss a dose, take the missed dose on the morning after you remember. Do not take two tablets on the same day. Return to taking one tablet once a week, as originally scheduled on your chosen day.

What happens if I overdose?

• The symptoms of an alendronate overdose are unknown, but the following symptoms might be expected: nausea, heartburn, pain in the abdomen, other stomach-related symptoms, muscle cramps, uncontrollable facial grimacing, seizures, irritability, and abnormal behavior.

What should I avoid while taking alendronate?

• Follow you doctor's recommendations about drinking alcohol and smoking. These activities are related to decreased bone density.

What are the possible side effects of alendronate?

Stop taking alendronate and seek emergency medical attention or contact your doctor immediately if you experience any of the following serious side effects:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• difficulty or pain when swallowing;
• chest pain;
• pain or burning under the ribs or in the back; or
• new or worsening heartburn.

Other, less serious side effects may be more likely to occur. Continue to take alendronate and talk to your doctor if you experience

• abdominal discomfort;
• stomach upset, nausea, vomiting, diarrhea, or constipation;
• headache;
• muscle, bone, or joint soreness or aches;
• eye pain;
• a rash; or
• an altered sense of taste.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect alendronate?

• Antacids and other medicines taken by mouth may decrease the effects of alendronate. Do not take any other medicines within 30 minutes after a dose of alendronate. Talk to your doctor before taking any other medicines during treatment with alendronate.
• Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen (Motrin, Advil, Nuprin, others), ketoprofen (Orudis KT, Orudis, Oruvail), indomethacin (Indocin, Indocin SR), naproxen (Anaprox, Aleve, Naprosyn), oxaprozin (Daypro), nabumetone (Relafen), piroxicam (Feldene), and others may increase the risk of damage to your stomach if they are taken during treatment with alendronate. Talk to your doctor before taking anti-inflammatory medications, pain relievers or fever reducers during treatment with alendronate.
• Drugs other than those listed here may also interact with alendronate. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Indocin
This page contains drug information on Indocin.
The information provided includes the following:
what is Indocin
the possible side effects of Indocin
what happens if you miss a dose of Indocin
what happens if you overdose with Indocin
the most important information about Indocin
how to use Indocin
other drugs that may affect Indocin
what to avoid while using Indocin

Generic Name: indomethacin (in doe METH a sin)
Brand Names: Indocin, Indocin SR

What is the most important information I should know about indomethacin?

• Take indomethacin with food, milk, or an antacid to lessen stomach upset.
• Do not break, crush, or chew the sustained-release formulations of indomethacin (e.g., Indocin SR). Swallow them whole.
• Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to indomethacin (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, indomethacin may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking indomethacin if you drink more than 3 alcoholic beverages a day.

What is indomethacin?

• Indomethacin is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Indomethacin works by reducing hormones that cause inflammation and pain in the body.
• Indomethacin is used to reduce the pain, inflammation, and stiffness caused by many conditions, such as osteoarthritis, rheumatoid arthritis, gout, ankylosing spondylitis, tendinitis, and bursitis.
• Indomethacin may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking indomethacin?

Before taking indomethacin, tell your doctor if you

• have an allergy to aspirin or any other NSAIDs,
• have an ulcer or bleeding in the stomach,
• drink more than three alcoholic beverages a day,
• have liver or kidney disease,
• have a coagulation (bleeding) disorder,
• have congestive heart failure,
• have fluid retention,
• have heart disease, or
• have high blood pressure.

You may not be able to take indomethacin, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Do not use indomethacin suppositories without first talking to your doctor if you have a history of inflammation of the rectum (proctitis) or if you have recently had rectal bleeding.

It is not known whether indomethacin taken early in pregnancy will be harmful to an unborn baby. Indomethacin must not be taken late in pregnancy (the third trimester) because it can affect the baby's heart. Do not take indomethacin without first talking to your doctor if you are pregnant or could become pregnant during treatment.

Indomethacin passes into breast milk and may affect a nursing baby. Do not take indomethacin without first talking to your doctor if you are breast-feeding a baby.

How should I take indomethacin?

• Take indomethacin exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take indomethacin with food, milk, or an antacid to lessen stomach upset.
• Do not break, crush, or chew the sustained-release formulations of indomethacin (e.g., Indocin SR). Swallow them whole.
• Shake the suspension well before measuring a dose. To ensure that you get a correct dose, measure the suspension with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
• Use the suppositories rectally as directed by your doctor. If you do not know how to properly use the suppository, ask your nurse, doctor, or pharmacist for instructions. Do not take the suppositories by mouth.
• Store indomethacin at room temperature away from moisture and heat. The suppositories and suspension can be stored at room temperature or in the refrigerator.

What happens if I miss a dose?

• If you are taking indomethacin on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.
• If you are taking indomethacin as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.
• Symptoms of an indomethacin overdose may include nausea, vomiting, stomach pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, sweating, numbness or tingling, little or no urine production, and slow breathing.

What should I avoid while taking indomethacin?

• Avoid prolonged exposure to sunlight. Indomethacin may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, indomethacin may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking indomethacin if you drink more than 3 alcoholic beverages a day.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to indomethacin (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of indomethacin?

Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.

If you experience any of the following serious side effects, stop taking indomethacin and seek medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• muscle cramps, numbness, or tingling;
• ulcers (open sores) in the mouth;
• rapid weight gain (fluid retention);
• seizures;
• decreased hearing or ringing in the ears;
• yellowing of the skin and eyes (jaundice); or
• abdominal cramping, indigestion, or heartburn.

Other, less serious side effects may be more likely to occur. Continue to take indomethacin and talk to your doctor if you experience

• dizziness or headache;
• nausea, gaseousness, diarrhea, or constipation;
• depression;
• fatigue or weakness;
• dry mouth; or
• irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect indomethacin?

Before taking indomethacin, tell your doctor if you are taking any of the following drugs:

• aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, others);
• another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Motrin, Advil, others), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Anaprox, others), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
• an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, indomethacin, or ketoprofen;
• an anticoagulant (blood thinner) such as warfarin (Coumadin);
• a steroid such as prednisone (Deltasone);
• insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), and others;
• probenecid (Benemid);
• lithium (Eskalith, Lithobid, others); or
• bismuth subsalicylate in drugs such as Pepto-Bismol.

You may not be able to take indomethacin, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with indomethacin. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Meticorten
This page contains drug information on Meticorten.
The information provided includes the following:
what is Meticorten
the possible side effects of Meticorten
what happens if you miss a dose of Meticorten
what happens if you overdose with Meticorten
the most important information about Meticorten
how to use Meticorten
other drugs that may affect Meticorten
what to avoid while using Meticorten

Generic Name: prednisone (PRED ni sone)
Brand Names: Deltasone, Liquid Pred, Meticorten, Orasone, Prednicen-M, Sterapred, Sterapred DS

What is the most important information I should know about prednisone?

• Do not stop taking prednisone suddenly if you have been taking it for a few weeks. You may need a gradual reduction in dosage before you stop taking this medication.
• Take prednisone with food or milk to lessen stomach upset.
• Carry some type of medical identification that will let others know you are taking prednisone in the case of an emergency.

What is prednisone?

• Prednisone is in a class of drugs called steroids. Prednisone reduces swelling and decreases the body's ability to fight infections.
• Prednisone is used to treat many different conditions. It is used to treat endocrine (hormonal) disorders when the body does not produce enough of its own steroids. It is also used to treat many disorders such as arthritis, lupus, severe psoriasis, severe asthma, ulcerative colitis, and Crohn's disease.
• Prednisone may also be used for purposes other than those listed in this medication guide.

Who should not take prednisone?

• Do not take prednisone if you have a serious bacterial, viral, or fungal infection. Prednisone weakens the body's immune response and thus its ability to fight infection.
• Before taking this medication, tell your doctor if you have
• kidney disease,
• liver disease,
• high blood pressure or heart disease,
• ulcerative colitis, diverticulitis, or stomach ulcers,
• hypothyroidism,
• a psychiatric condition,
• osteoporosis,
• myasthenia gravis,
• diabetes mellitus, or
• any other medical conditions.
• You may not be able to take prednisone, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• Prednisone is in the FDA pregnancy category C. This means that it is not known whether prednisone will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
• Prednisone passes into breast milk. Do not take prednisone without first talking to your doctor if you are breast-feeding a baby.

How should I take prednisone?

• Take prednisone exactly as directed by your doctor. Do not take more or less than is prescribed for you. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take prednisone with food or milk to lessen stomach upset.
• Measure the liquid with the dropper provided or with a special dose-measuring spoon or cup. Ask your pharmacist for a dose-measuring spoon or cup if you do not have one.
• If you are taking one dose daily, take that dose before 9 a.m. if possible, to follow the body's natural cycle. If you take more than one dose daily, space the doses evenly throughout the day as directed by your doctor.
• Do not stop taking prednisone suddenly if you have been taking it for a few weeks. You may need a gradual reduction in dosage before you stop taking this medication.
• Carry some type of medical identification that will let others know you are taking prednisone in the case of an emergency.
• Store prednisone at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you take one dose daily, take the missed dose as soon as you remember. However, if you don't remember until the next day, skip the dose you missed and take only your regular daily dose.
• If you take more than one dose daily, you can either take the missed dose as soon as you remember, or you can take two doses at the next dose time.
• If you take one dose every other day, take the missed dose as soon as you remember, then go back to your regular every-other-day schedule.

What happens if I overdose?

• Seek emergency medical attention. A single large dose of this medication is unlikely to cause symptoms or death. An overdose is more likely to be caused by a chronic overdose--large doses taken over a period of time.
• Symptoms of an overdose include obesity (especially around the stomach); a round face; increased hair growth (especially around the face); acne; bruising; increased blood pressure; swollen hands, feet, or ankles (fluid retention); and sore or weak muscles.

What should I avoid while taking prednisone?

• Avoid alcohol. Acting together, alcohol and prednisone can be damaging to the stomach.
• Avoid sources of infection. Wash your hands frequently and keep them away from the mouth and eyes. Your immune system may be weakened while taking prednisone.
• Do not receive any immunizations during treatment with prednisone without first talking to your doctor.

What are the possible side effects of prednisone?

If you experience any of the following serious side effects, stop taking prednisone and seek emergency medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
• increased blood pressure (severe headache or blurred vision); or
• sudden weight gain (more than 5 pounds in a day or two).

Other, less serious side effects may be more likely to occur. Continue to take prednisone and talk to your doctor if you experience

• insomnia;
• nausea, vomiting, or stomach upset;
• fatigue or dizziness;
• muscle weakness or joint pain;
• problems with diabetes control; or
• increased hunger or thirst.

Other side effects that occur only rarely, usually with high doses of prednisone, include

• acne,
• increased hair growth,
• thinning of the skin,
• cataracts,
• glaucoma,
• osteoporosis,
• roundness of the face, and
• changes in behavior.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect prednisone?

• Do not take any other over-the-counter or prescription medications, including herbal products, during treatment with prednisone without first talking to your doctor. Many other medicines can interact with prednisone resulting in side effects or altered effectiveness of the medications.

Mobic This page contains drug information on Mobic. The information provided includes the following: what is Mobic the possible side effects of Mobic what happens if you miss a dose of Mobic what happens if you overdose with Mobic the most important information about Mobic how to use Mobic other drugs that may affect Mobic what to avoid while using Mobic

Generic Name: meloxicam (me LOCK seh cam) Brand Names: Mobic

What is the most important information I should know about meloxicam?

• Contact your doctor if you experience bloody, black, or tarry stools, blood in your vomit; swelling or rapid weight gain (fluid retention); unusual fatigue or weakness; yellowing of the skin or eyes; excessive itching; flu-like symptoms; or abdominal pain or tenderness. These symptoms could indicate serious side effects.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to meloxicam (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, meloxicam may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking meloxicam if you drink more than 3 alcoholic beverages a day.

What is meloxicam?

• Meloxicam is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Meloxicam works by reducing hormones that cause inflammation and pain in the body.
• Meloxicam is used to reduce the pain, inflammation, and stiffness caused by osteoarthritis and rheumatoid arthritis.
• Meloxicam may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking meloxicam?

Before taking this medication, tell your doctor if you

• have an allergy to aspirin or any other NSAIDs,
• have an ulcer or bleeding in your stomach,
• drink more than three alcoholic beverages a day,
• have liver disease;
• have kidney disease;
• have a bleeding or blood clotting disorder,
• have congestive heart failure,
• have fluid retention,
• have heart disease, or
• have high blood pressure.

You may not be able to take meloxicam, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Meloxicam is in the FDA pregnancy category C. This means it is not known whether meloxicam will be harmful to an unborn baby. Meloxicam should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take meloxicam without first talking to your doctor if you are pregnant or could become pregnant during treatment.

It is not known whether meloxicam passes into breast milk. Do not take this medication without first talking to your doctor if you are breast-feeding a baby.

How should I take meloxicam?

• Take meloxicam exactly as directed. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Meloxicam may be taken with or without food.
• Store meloxicam at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you are taking meloxicam on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.
• If you are taking meloxicam as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a meloxicam overdose include nausea, vomiting, stomach pain, loss of consciousness, drowsiness, headache, cardiac arrest, stomach pain, seizures, little or no urine production, and slow breathing.

What should I avoid while taking meloxicam?

• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, meloxicam may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking meloxicam if you drink more than 3 alcoholic beverages a day.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to meloxicam (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of meloxicam?

Contact your doctor if you experience bloody, black, or tarry stools, blood in your vomit; swelling or rapid weight gain (fluid retention); unusual fatigue or weakness; yellowing of the skin or eyes; excessive itching; flu-like symptoms; or abdominal pain or tenderness. These symptoms could indicate serious side effects.

If you experience any of the following serious side effects, stop taking meloxicam and seek medical treatment or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• muscle cramps, numbness, or tingling;
• ulcers (open sores) in the mouth;
• seizures;
• decreased hearing or ringing in the ears; or
• abdominal cramping, heartburn, or indigestion.

Other, less serious side effects may be more likely to occur. Continue to take meloxicam and talk to your doctor if you experience

• dizziness or headache;
• nausea, diarrhea, or constipation;
• depression;
• fatigue or weakness;
• dry mouth; or
• irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect meloxicam?

Before taking meloxicam, tell your doctor if you are taking any of the following drugs:

• aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, others);
• another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), ibuprofen (Motrin, Advil, others), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), naproxen (Aleve, Anaprox, Naprosyn, Naprelan, others), nabumetone (Relafen), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
• an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, meloxicam, or ketoprofen;
• a diuretic such as furosemide (Lasix), bumetanide (Bumex), ethacrynic acid (Edecrin), torsemide (Demadex), hydrochlorothiazide (HCTZ, HydroDiuril, Microzide), chlorothiazide (Diuril), chlorthalidone (Hygroton, Thalitone), indapamide (Lozol), metolazone (Mykrox, Zaroxolyn), and others;
• an anticoagulant (blood thinner) such as warfarin (Coumadin); or
• lithium (Eskalith, Lithobid, others); or

You may not be able to take meloxicam, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with meloxicam. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Motrin
This page contains drug information on Motrin.
The information provided includes the following:
what is Motrin
the possible side effects of Motrin
what happens if you miss a dose of Motrin
what happens if you overdose with Motrin
the most important information about Motrin
how to use Motrin
other drugs that may affect Motrin
what to avoid while using Motrin

Generic Name: ibuprofen (eye byoo PROE fen)
Brand Names: Advil, Ibu-Tab, Midol IB, Motrin, Nuprin, Pediacare Fever, Rufen

What is the most important information I should know about ibuprofen?

• Take ibuprofen with food, milk, or an antacid to lessen stomach upset.
• Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to ibuprofen (such as naproxen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, ibuprofen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking ibuprofen if you drink more than 3 alcoholic beverages a day.

What is ibuprofen?

• Ibuprofen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.
• Ibuprofen is used to reduce the fever, pain, inflammation, and stiffness caused by many conditions, such as osteoarthritis, rheumatoid arthritis, and abdominal cramps associated with menstruation.
• Ibuprofen may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking ibuprofen?

• Before taking ibuprofen, tell your doctor if you
• have an allergy to aspirin or any other NSAIDs,
• have an ulcer or bleeding in the stomach,
• drink more than three alcoholic beverages a day,
• have liver or kidney disease,
• have a coagulation (bleeding or blood clotting) disorder,
• have congestive heart failure,
• have fluid retention,
• have heart disease, or
• have high blood pressure.
• You may not be able to take ibuprofen, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
• During the first two trimesters of pregnancy ibuprofen is in the FDA pregnancy category B. This means that it is unlikely to harm an unborn baby during the first two trimesters of pregnancy. However, ibuprofen should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take ibuprofen without first talking to your doctor if you are pregnant or could become pregnant during treatment.
• Ibuprofen passes into breast milk in very small amounts, however it is not expected to be harmful to a nursing baby. Talk to your doctor before taking ibuprofen if you are breast-feeding.

How should I take ibuprofen?

• Take ibuprofen exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you
• Take each dose with a full glass of water.
• Take ibuprofen with food, milk, or an antacid to lessen stomach upset.
• Shake the suspension well before measuring a dose. To ensure that you get the correct dose, measure the liquid form of ibuprofen with a special dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.
• Store ibuprofen at room temperature away from moisture and heat.

What happens if I miss a dose?

• If you are taking ibuprofen on a regular schedule, take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose.
• If you are taking ibuprofen as needed, take the missed dose if it is needed, then wait the recommended or prescribed amount of time before taking another dose.

What happens if I overdose?

• Seek emergency medical attention if an overdose is suspected.
• Symptoms of a ibuprofen overdose may include nausea, vomiting or stomach pain, dizziness, drowsiness, headache, ringing in the ears, blurred vision, seizures, sweating, numbness or tingling, little or no urine production, and slow breathing.

What should I avoid while taking ibuprofen?

• Avoid prolonged exposure to sunlight. Ibuprofen may increase the sensitivity of the skin to sunlight. Use a sunscreen and wear protective clothing when exposure to the sun is unavoidable.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, ibuprofen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking ibuprofen if you drink more than 3 alcoholic beverages a day.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to ibuprofen (such as naproxen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.

What are the possible side effects of ibuprofen?

Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.

If you experience any of the following serious side effects, stop taking ibuprofen and seek medical attention or contact your doctor immediately:

• an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
• muscle cramps, numbness, or tingling;
• ulcers (open sores) in the mouth;
• rapid weight gain (fluid retention);
• seizures;
• decreased hearing or ringing in the ears;
• yellowing of the skin and eyes (jaundice); or
• abdominal cramping, indigestion, or heartburn.

Other, less serious side effects may be more likely to occur. Continue to take ibuprofen and talk to your doctor if you experience

• dizziness or headache;
• nausea, gaseousness, diarrhea, or constipation;
• depression;
• fatigue or weakness;
• dry mouth; or
• irregular menstrual periods.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect ibuprofen?

Before taking ibuprofen, tell your doctor if you are taking any of the following drugs:

• aspirin or another salicylate (form of aspirin) such as salsalate (Disalcid), diflunisal (Dolobid), choline salicylate-magnesium salicylate (Trilisate, Tricosal, others), and magnesium salicylate (Doan's, others);
• another nonsteroidal anti-inflammatory drug (NSAID) such as diclofenac (Cataflam, Voltaren), etodolac (Lodine), fenoprofen (Nalfon), flurbiprofen (Ansaid), indomethacin (Indocin), ketoprofen (Orudis, Orudis KT), ketorolac (Toradol), meloxicam (Mobic), nabumetone (Relafen), naproxen (Aleve, Naprosyn, Anaprox, others), oxaprozin (Daypro), piroxicam (Feldene), sulindac (Clinoril), or tolmetin (Tolectin);
• an over-the-counter cough, cold, allergy, or pain medicine that contains aspirin, ibuprofen, ibuprofen, or ketoprofen;
• an anticoagulant (blood thinner) such as warfarin (Coumadin);
• a steroid such as prednisone (Deltasone);
• insulin or an oral diabetes medicine such as glipizide (Glucotrol), glyburide (Diabeta, Micronase), and others;
• probenecid (Benemid);
• lithium (Eskalith, Lithobid, others); or
• bismuth subsalicylate in drugs such as Pepto-Bismol.

You may not be able to take ibuprofen, or you may require a dosage adjustment or special monitoring during treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with ibuprofen. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products.

Naprosyn
This page contains drug information on Naprosyn.
The information provided includes the following:
what is Naprosyn
the possible side effects of Naprosyn
what happens if you miss a dose of Naprosyn
what happens if you overdose with Naprosyn
the most important information about Naprosyn
how to use Naprosyn
other drugs that may affect Naprosyn
what to avoid while using Naprosyn

Generic Name: naproxen (na PROX en)
Brand Names: Aleve, Aleve Caplet, Anaprox, Anaprox-DS, EC Naprosyn, Naprelan, Naprosyn

What is the most important information I should know about naproxen?

• Take naproxen with food, milk, or an antacid to lessen stomach upset.
• Do not crush or chew the extended-release forms of naproxen (e.g., Naprelan, EC Naprosyn, others). Swallow them whole. These are specially formulated to release slowly in the body. Ask your pharmacist if you do not know if you have an extended-release formulation.
• Contact your doctor if you experience blood in vomit or bloody, black, or tarry stools. These symptoms could indicate damage to the stomach or intestines, which could be dangerous.
• Many over-the-counter cough, cold, allergy, and pain medicines contain aspirin or other medicines similar to naproxen (such as ibuprofen, ketoprofen, and others). Before taking any prescription or over-the-counter medicine, talk to your doctor and pharmacist.
• Patients who are taking over-the-counter naproxen products (Aleve) should follow the instructions on the label. Do not exceed the recommended over-the-counter doses for naproxen (220 milligrams twice daily) and do not take naproxen for longer than ten days unless a physician directs otherwise.
• Avoid alcohol or use it with moderation. If you drink more than three alcoholic beverages a day, naproxen may increase the risk of dangerous stomach bleeding. Talk to your doctor before taking naproxen if you drink more than 3 alcoholic beverages a day.
• Use caution when driving, operating machinery, or performing other hazardous activities. Naproxen may cause dizziness. If you experience dizziness, avoid these activities.

What is naproxen?

• Naproxen is in a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen works by reducing hormones that cause inflammation and pain in the body.
• Naproxen is used to reduce pain, inflammation, and stiffness caused by many conditions, such as osteoarthritis, rheumatoid arthritis, gout, ankylosing spondylitis, injury, abdominal cramps associated with menstruation, tendinitis, and bursitis.
• Naproxen may also be used for purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking naproxen?

Before taking this medication, tell your doctor if you

• have an allergy to aspirin or any other NSAIDs,
• have an ulcer or bleeding in your stomach,
• drink more than three alcoholic beverages a day,
• have liver disease,
• have kidney disease,
• have a coagulation (bleeding) disorder,
• have congestive heart failure,
• have fluid retention,
• have heart disease, or
• have high blood pressure.

You may not be able to take naproxen, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.

Naproxen is in the FDA pregnancy category B. This means that it is not expected to be harmful to an unborn baby. Naproxen should not be taken late in pregnancy (the third trimester) because a similar drug is known to affect the baby's heart. Do not take naproxen without first talking to your doctor if you are pregnant.

Naproxen passes into breast milk and may affect a nursing infant. Do not take this medicine without first talking to your doctor if you are breast-feeding a baby.

How should I take naproxen?

• Take naproxen exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
• Take each dose with a full glass of water.
• Take naproxen with milk, food, or an antacid to lessen stomach upset.
• Do not crush or chew the extended-release forms of naproxen (e.g., Naprelan, EC Naprosyn, others). Swallow them whole. These are specially formulated to release slowly in the body. Ask your pharmacist if you do not know if you have an extended-release formulation.
• Patients who are taking over-the-counter naproxen products (Aleve) should follow the